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Precision Prevention

Rebbeck TR, Lynch HT, Neuhausen SL, Narod SA, Van ‘t Veer L, Garber JE, Evans G, Isaacs C, Daly MB, Matloff E, Olopade OI, Weber BL for The PROSE Study Group (2002) Reduction in Cancer Risk After Bilateral Prophylactic Oophorectomy in BRCA1 and BRCA2 Mutation Carriers. New England Journal of Medicine, 346:1616-1622.

Rebbeck TR, Friebel T, Lynch HT, Neuhausen SL, van ‘t Veer L, Garber JE, Evans GR, Narod SA, Isaacs C, Matloff E, Daly MB, Olopade OI, Weber BL (2004) Bilateral Prophylactic Mastectomy Reduces Breast Cancer Risk In BRCA1 and BRCA2 Mutation Carriers. Journal of Clinical Oncology, 22(6):1055-62.

Rebbeck TR, Friebel T, Wagner T, Lynch HT, Garber JE, Daly MB, Isaacs C, Olopade OI, Neuhausen SL, Van ‘t Veer L, Eeles R, Evans DG, Tomlinson G, Matloff E, Narod SA, The PROSE Study Group, Eisen A, Domchek S, Armstrong K, Weber BL (2005) Effect of Short-Term Hormone Replacement Therapy on Breast Cancer Risk Reduction After Bilateral Prophylactic Oophorectomy in BRCA1 And BRCA2 Mutation Carriers. Journal of Clinical Oncology, 23(31):7804-10.

Domchek SM, Friebel TM, Neuhausen SL, Wagner T, Evans G, Isaacs C, Garber JE, Daly MB, Eeles R, Matloff E, Tomlinson GE, Van ‘t Veer L, Lynch HT, Olopade OI, Weber BL, Rebbeck TR (2006) Mortality Reduction After Risk-Reducing Bilateral Salpingo-Oophorectomy In A Prospective Cohort of BRCA1 AndBRCA2 Mutation Carriers. Lancet Oncology, 7(3):223-9.

Domchek SM, Friebel TM, Singer CF, Evans DG, Lynch HT, Isaacs C, Garber JE, Neuhausen SL, Matloff E, Eeles R, Pichert G, van t’Veer L, Tung N, Weitzel JN, Couch FJ, Rubinstein WS, Ganz PA, Daly MB, Olopade OI, Tomlinson G, Schildkraut J, Blum JL, Rebbeck TR (2010) Association of Risk-Reducing Surgery in BRCA1or BRCA2 Mutation Carriers with Cancer Risk and Mortality, JAMA, 304(9):967-75.

Rebbeck TR (2014) Precision Prevention of Cancer. Cancer Epidemiology Biomarkers and Prevention, 23(12):2713-5.

 

Rebbeck TR, Burns-White K, Chan AT, Emmons K, Freedman M, Hunter DJ, Kraft P, Laden F, Mucci L, Parmigiani G, Schrag D, Syngal S, Tamimi RM, Viswanath K, Yurgelun MB, Garber JE (2018) Precision Prevention and Early Detection of Cancer: Fundamental Principles. Cancer Discovery, 8(7):803-811.

Castle PE, Faupel-Badger JM, Umar A, Rebbeck TR (2024) Proposed Framework and Lexicon for Cancer Prevention, Cancer Discovery, 14(4):594-599.

 

Cancer Etiology, Interception, and Disparities

Rebbeck TR, Sankar P (2005) Ethnicity, Ancestry, and Race in Molecular Epidemiological Research. Cancer Epidemiology, Biomarkers and Prevention, 14(11 Pt 1):2467-71.

Rebbeck TR, Haas G (2014) Temporal Trends and Racial Disparities in Global Prostate Cancer Prevalence. Canadian Journal of Urology, 21(5):7496-506.

Rebbeck TR, Mitra N, Wan F, Sinilnikova O, Healey S, McGuffog L, Mazoyer S, Chenevix-Trench G, Easton DE, Antoniou AC, Nathanson KL, and the CIMBA Consortium (2015) Association of Type and Location of BRCA1 and BRCA2 Mutations with Risk of Breast and Ovarian Cancer, JAMA, 313(13):1347-61. 

Yamoah K, Deville C, Vapiwala N, Spangler E, Zeigler-Johnson CM, Malkowicz B, Lee DI, Kattan M, Dicker AP, Rebbeck TR (2015) African American men with low-grade prostate cancer have increased disease recurrence after prostatectomy compared with Caucasian men. Urologic Oncology 33(2):70.e15-22.

Lachance J, Berens AJ, Hansen MEB, Teng AK, Tishkoff SA, Rebbeck TR (2018) Genetic hitchhiking and population bottlenecks contribute to prostate cancer disparities in men of African descent. Cancer Research, 8(9):2432-2443.

Friebel TM, Andrulis IL, Balmaña J, Blanco AM, Couch FJ, Daly MB, Domchek SM, Easton DF, Foulkes WD, Ganz PA, Garber J, Glendon G, Greene MH, Hulick PJ, Isaacs C, Jankowitz RC, Karlan BY, Kirk J, Kwong A, Lee A, Lesueur F, Lu KH, Nathanson KL, Neuhausen SL, Offit K, Palmero EI, Sharma P, Tischkowitz M, Toland AE, Tung N, van Rensburg EJ, Vega A, Weitzel JN, GEMO Study Collaborators, Hoskins KF, Maga T, Parsons MT, McGuffog L, Antoniou AC, Chenevix-Trench G, Huo D, Olopade OI, Rebbeck TR (2019) BRCA1 and BRCA2 Pathogenic Sequence Variants in Women of African Origin or Ancestry. Human Mutation, 40(10);1781-1796.

Mahal BA, Alshalalfa M, Kensler KH, Chowdhury-Paulino I, Schaeffer EM, Spratt D, Yamoah K, Nguyen PL, Mucci LA, Kantoff P, Rebbeck TR (2020) Racial differences in genomic profiling of prostate cancer: Implications for disparities in the precision oncology era, New England Journal of Medicine, 383(11):1083-1085.

Kensler KH, Pernar CH, Mahal BA, Nguyen PL, Trinh QD, Kibel AS, Rebbeck TR (2020) Racial/ethnic variation in PSA testing and prostate cancer incidence following the 2012 U.S.P.S.T.F. recommendation. Journal of the National Cancer Institute, 113(6):719-726. 

Kensler KH, Awasthi S, Alshalalfa M, Trock BJ, Freedland SJ, Freeman MR, You S, Mahal BA, Den RB, Dicker AP, Karnes RJ, Klein EA, Lal P, Liu Y, Davicioni E, Rayford W, Yamoah K, Rebbeck TR (2022) Variation in Molecularly Defined Prostate Tumor Subtypes by Self-identified Race. European Urology Open Science. 40:19-26.

Crosby D, Bhatia S, Brindle KM, Coussens LM, Dive C, Emberton M, Esener S, Fitzgerald RC, Gambhir SS, Kuhn P, Rebbeck TR, Balasubramanian S (2022) Early detection of cancer. Science 18;375(6586):eaay9040. 

Rebbeck TR, Mahal B, Maxwell KN, Garraway IP, Yamoah K (2022) Race and Genetic Ancestry Are Different, But Both Affect Health, Nature Medicine, 28(5):890-893.

Kensler KH, Johnson R, Morley F, Albrair M, Dickerman BA, Gulati R, Holt SK, Iyer HS, Kibel AS, Lee JR, Preston MA, Vassy JL, Wolff EM, Nyame YA, Etzioni R, Rebbeck TR (2023) Prostate Cancer Screening in African American Men: A Review of the Evidence. Journal of the National Cancer Institute, 116(1):34-52.

Manirakiza AV, Baichoo S, Uwineza A, Dukundane D, Uwinkindi F, Ngendahayo E, Rubagumya F, Muhawenimana E, Nsabimana N, Nzeyimana I, Maniragaba T, Ntirenganya F, Rurangwa E, Mugenzi P, Mutamuliza J, Runanira D, Niyibizi BA, Rugengamanzi E, Besada J, Nielsen SM, Bucknor B, Nussbaum RL, Koeller D, Andrews C, Mutesa L, Fadelu T, Rebbeck TR (2024) Germline sequence variation in cancer genes in Rwandan breast and prostate cancer cases. NPJ Genomic Medicine, I9(1):61.

Janivara R, Chen WC, Hazra U, Baichoo S, Agalliu I, Kachambwa P, Simonti CN, Brown LM, Tambe SP, Kim MS, Harlemon M, Jalloh M, Muzondiwa D, Naidoo D, Ajayi OO, Snyper NY, Niang L, Diop H, Ndoye M, Mensah JE, Abrahams AOD, Biritwum R, Adjei AA, Adebiyi AO, Shittu O, Ogunbiyi O, Adebayo S, Nwegbu MN, Ajibola HO, Oluwole OP, Jamda MA, Pentz A, Haiman CA, Spies PV, van der Merwe A, Cook MB, Chanock SJ, Berndt SI, Watya S, Lubwama A, Muchengeti M, Doherty S, Smyth N, Lounsbury D, Fortier B, Rohan TE, Jacobson JS, Neugut AI, Hsing AW, Gusev A, Aisuodionoe-Shadrach OI, Joffe M, Adusei B, Gueye SM, Fernandez PW, McBride J, Andrews C, Petersen LN, Lachance J, Rebbeck TR (2024) Heterogeneous Genetic Architectures and Evolutionary Genomics of Prostate Cancer in Sub-Saharan Africa. Nature Genetics, 56(10):2093-2103.

 

Global Health

Gueye SM, Zeigler-Johnson CM, Friebel T, Spangler E, Jalloh M, MacBride S, Malkowicz SB, Rebbeck TR (2003) Clinical Characteristics of Prostate Cancer in African Americans, American Caucasians and Senegalese Men. Urology, 61:987-992.

Stefflova K, Dulik MC, Barnholtz-Sloan J, Pai AA, Walker AH, Rebbeck TR (2011) Dissecting the Within-Africa Ancestry of Populations of African Descent in the Americas, PLoSONE 6(1): e14495. 

Rebbeck TR (2013) Handbook for Cancer Research in Africa, Brazzaville: WHO Press. (Reprinted 2015); Rebbeck TR (2013) Guide de la Recherche Sur le Cancer en Afrique, Brazzaville: WHO Press; Rebbeck TR (2013) Manual de Investigação de Cancro em África, Brazzaville: WHO Press.

Andrews C, Fortier B, Hayward A, Lederman R, Petersen L, McBride J, Petersen DC, Ajayi O, Kachambwa P, Seutloali M, Shoko A, Mokhosi M, Hiller R, Adams M, Ongaco C, Pugh E, Romm J, Shelford T, Chinegwundoh F, Adusei B, Mante S, Snyper NY, Agalliu I, Lounsbury DW, Rohan T, Orfanos A, Quintana Y, Jacobson JS, Neugut AI, Gelmann E, Lachance J, DialC, Diallo TA, Jalloh M, Gueye SM, Sène Kane PM, Diop H, Ndiaye AJ, Sall AS, Toure-Kane NC, Onyemata E, Abimiku A, Adjei AA, Biritwum R, Gyasi R, Kyei M, Mensah JE, Okine J, Okyne V, Rockson I, Tay E, Tettey Y, Yeboah E, Chen WC, Singh E, Cook MB, Martin D, Duffy CN, Hsing A, Soo C, Fernandez P, Irusen H, Aisuodionoe-Shadrach O, Jamda AM, Olabode PO, Nwegbu MM, Ajibola OH, Ajamu OJ, Ambuwa YG, Adebiyi AO, Asuzu M, Ogunbiyi O, Popoola O, Shittu O, Amodu O, Odiaka E, Makinde I, Joffe M, Pentz A, Rebbeck TR (2018) Development, Evaluation, and Implementation of a Pan-African Cancer Research Network: Men of African Descent and Carcinoma of the Prostate (MADCaP). Journal of Global Oncology, 4:1-14.

Odiaka E, Lounsbury DW, Jalloh M, Adusei B, Diallo TA, Sene Kane PM, Rockson I, Okyne V, Irusen H, Pentz A, Makinde I, Ajibola OH, Petersen L, McBride J, Mante S, Agalliu I, Adebiyi AO, Popoola O, Yeboah E, Mensah JE, Hsing A, Fernandez P, Aisuodionoe-Shadrach O, Joffe M, Singh E, Gueye SM, Quintana Y, Fortier B, Rebbeck TR, Andrews C (2018) Effective Project Management for Health Research Initiatives in Low and Middle-Income Countries. Journal of Global Oncology, 4:1-14.

Rebbeck TR (2020) Cancer in Sub-Saharan Africa. Science, 367(6473):27-28.

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